Levitra

Levitra (Vardenafil)

Erectile dysfunction (inability to attain or maintain an erection necessary for sexual intercourse).

Usual is 10 mg. Accepted for 25-60 minutes before sexual intercourse. The maximum recommended dosing frequency - 1 time per day. Depending on the efficacy and tolerability of treatment the dose may be increased to 20 mg or decreased to 5 mg per day. The maximum recommended dose is 20 mg 1 time a day. The dose of 5 mg is recommended in elderly patients (over 65). Dose of 20 mg is appointed in cases of severe ED (diabetes, prostatectomy) when the starting dose of 10 mg is not effective enough. Eating and drinking do not affect the effectiveness of vardenafil. Levitra is effective only when a sufficient level of sexual stimulation. The duration of action Levitra is 4-5 hours.

Erection of the penis is a hemodynamic process based on the relaxation of smooth muscles of cavernous bodies and located in its arterioles. During sexual stimulation of the nerve endings of cavernous bodies released nitric oxide (N0), activating the enzyme guanylate cyclase, which leads to higher content in the cavernous bodies of cyclic guanosine monophosphate (cGMP). The result is relaxation of smooth muscles of cavernous bodies, which increases blood flow to the penis.
By blocking specific phosphodiesterase fifth type (PDE5), which participates in the cleavage of cGMP, Vardenafil, thus enhances the local action of endogenous nitric oxide (N0) in the cavernous bodies during sexual stimulation. This effect causes the ability of vardenafil to strengthen the response to sexual stimulation.

Levitra is to be used as needed, so you are not likely to miss a dose.

Store at 25 degrees C (77 degrees F); excursions permitted to 15-30 degrees C (59-86 degrees F). Keep Levitra and all medicines out of the reach of children and away from moisture and heat.

Hypersensitivity to any component of the drug. The simultaneous use of nitrates or drugs, which are nitric oxide donators. Combination with HIV protease inhibitors such as indinavir or ritonavir. Levitra is not indicated for women and children under 16. Caution should be used in patients: with congenital QT prolongation, with anatomical deformation of the penis (curved, cavernous fibrosis, Peyronie's disease), diseases predisposing to priapism (sickle cell anemia, multiple myeloma, leukemia) with severe impairment the liver. In patients with impaired liver function minor changes in dosing is required. In patients with moderate hepatic impairment initial dose is 5 mg per day. In the future, depending on the efficacy and tolerability of treatment the dose may be increased to a maximum of 10 mg of kidney disease in the terminal stage. In patients with low, moderate and severe reduction in kidney function change the dosage is not required; with hypotension (systolic blood pressure at rest below 90 mm Hg. Art.) With recent stroke and myocardial infarction, with unstable angina, a hereditary degenerative diseases the retina (eg retinitis pigmentosa) with a tendency to bleeding and exacerbation of peptic ulcer disease, with aortic stenosis and idiopathic hypertrophic stenosis subaortalnym

Vardenafil (Levitra) is generally well tolerated, side effects are usually slightly or moderately expressed and are transient in nature. The most common (1-10%): headache, facial flushing, indigestion, nausea, dizziness, rhinitis. Unusual and rare (0.1-1%): face edema, photosensitivity, pain, hypertension, changes in functional "liver" tests, increased GGT, increased creatine kinase, myalgia, drowsiness, dyspnea, blurred vision, watery eyes , priapism, anaphylactic reaction (including laryngeal edema), angina pectoris, hypotension, myocardial ischemia, postural hypotension, syncope, increased muscle tone, nasal bleeding, glaucoma.

Levitra is available with a prescription under the brand name Levitra. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new for you.